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In some cases, however, antidepressants cause side effects that don't go away. Fluoxetine (Prozac) Escitalopram (Lexapro) Fluvoxamine (Luvox) Paroxetine (Paxil) TCAs TCA antidepressants are prescribed much less than they used to be. We explain how it works and why it may help treat anxiety Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Others still have suggested that emotional blunting is more of a symptom revealed, 9 meaning that once the antidepressants are. Selective norepinephrine reuptake inhibitors (SNRIs) such as Cymbalta (duloxetine), Pristiq (desvenlafaxine), and Effexor XR (venlafaxine) Selective serotonin reuptake inhibitors (SSRIs) like Lexapro (escitalopram), Prozac (fluoxetine), Zoloft (sertraline), and Paxil (paroxetine). However, antidepressant use in children and teens must be monitored carefully, as rarely there can be severe side effects. 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